Journal: Current Oncology

Article Title: DXA-Derived Visceral and Subcutaneous Adipose Tissue and Postmenopausal Breast Cancer Mortality

doi: 10.3390/curroncol33020119

Figure Lengend Snippet: Multivariable-adjusted associations between ( A ) baseline and ( B ) time-varying adiposity variables and breast cancer-related mortality in the Women’s Health Initiative dual-energy X-ray absorptiometry cohort ( n = 9767; breast cancer-related deaths: 87). VAT, SAT, and TAT per 100 cm 2 are limited to the new 5 cm high abdominal region of interest. Multivariable models adjusted for: age at baseline, region, education, income, race and ethnicity, hormone therapy trial arm, diet modification trial arm, calcium and vitamin D trial arm, height at baseline, alcohol intake, smoking status, physical activity (MET-hrs/wk), physical function (SF 36 score), total energy intake (kcal/day), HEI-2015 score, hormone therapy, aspirin, metformin, female relative with breast cancer, age at menarche, age at first birth, total number of months of breastfeeding, age at menopause, and surgical menopause. VAT: Visceral adipose tissue; SAT: Abdominal subcutaneous adipose tissue; TAT: Total abdominal adipose tissue; Q: Quartile; SHR: Sub-hazard ratio; CI: Confidence interval; WHI: Women’s Health Initiative; DXA: Dual-energy X-ray absorptiometry.

Article Snippet: In short, DXA scans (QDR2000, 2000+, or 4500W DXA models and QDR software v12.1, Hologic Inc., Bedford, MA, USA) were performed to measure total and regional adiposity and lean soft tissue at baseline, Year 3, and Year 6 [ ].

Techniques: Modification, Activity Assay